CADM1 Recombinant Protein

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ProSci
Product Code: PSI-96-071
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-96-071-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Documents

Further Information

Additional Names:
CADM1, BL2, IGSF4, IGSF-4, IGSF4A, NECL2, Necl-2, RA175, ST17, SYNCAM, TSLC1, sTSLC-1, sgIGSF, synCAM1, DKFZp686F1789, MGC149785, MGC51880
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Cell Adhesion Molecules (CAMs) are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix (ECM) in the process called cell adhesion. Cell adhesion molecule 1 is a single-pass type I membrane protein which belongs to the?nectin family. Cell Adhesion Molecule 1 contains two?Ig-like C2-type (immunoglobulin-like) domains and one?Ig-like V-type (immunoglobulin-like) domain, and is also known as CADM1; BL2; DKFZp686F1789; IGSF4; IGSF4A; MGC149785; MGC51880; NECL2; Necl-2; RA175; ST17; SYNCAM; TSLC1; sTSLC-1; sgIGSF; synCAM1. CADM1 mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. CADM1 may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. CADM1 may play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
Background References:
  • Kuramochi M. 2001, Nat. Genet. 27: 427-430 .
  • Yageta M. et al., 2002, Cancer Res. 62: 5129-5133.
  • Furuno T. et al., 2005, J. Immunol. 174: 6934-6942.
  • Boles KS. et al., 2005, Blood. 106: 779-786.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
23705
NCBI Official Name:
cell adhesion molecule 1
NCBI Official Symbol:
CADM1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
37.9 kDa
Protein Accession #:
NP_055148.3
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9BY67