Delta 4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-241-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
Delta 4, DLL4
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
Background References:
- Del Barrio M.G., et al., 2007, Development 134:3427-3436.
- Brutsch R., et al., 2010, Circ. Res. 107:592-601.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
54567
NCBI Official Name:
delta-like 4 (Drosophila)
NCBI Official Symbol:
DLL4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
55.1 kDa
Protein Accession #:
AAI06951
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9NR61