NTRK2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-564-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
NTRK2, TRKB, GP145-TrkB
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Neurotrophic tyrosine kinase receptor type 2 (NTRK2) is also known as BDNF/NT-3 growth factors receptor, Tropomyosin-related kinase B (TRKB) and TrkB tyrosine kinase, which belongs to the protein kinase superfamily or Tyr protein kinase family. Insulin receptor subfamily. NTRK2 / TrkB contains two Ig-like C2-type (immunoglobulin-like) domains, two LRR (leucine-rich) repeats, one LRRCT domain, one LRRNT domain, one protein kinase domain. NTRK2 / Trk-B is expressed in the central and peripheral nervous system. The catalytic activity of NTRK2 is ?ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate?. NTRK2 / TrkB involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity.
Background References:
- Allen S.J., et al., 1994, Neuroscience 60:825-834.
- Stoilov P., et al., 2002, Biochem. Biophys. Res. Commun. 290:1054-1065.
- Meakin S.O., et al., 1999, J. Biol. Chem. 274:9861-9870.
- Yeo G.S., et al., 2004, Nat. Neurosci. 7:1187-1189.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
4915
NCBI Official Name:
neurotrophic tyrosine kinase, receptor, type 2
NCBI Official Symbol:
NTRK2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
45 kDa
Protein Accession #:
AAH31835
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q16620