CGP 39 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-186-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CHI3L1, YKL-40, CGP-39, GP-39, hCGP-39, ASRT7
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Chitinase-3-like protein 1 (CHI3L1) is also known as Cartilage glycoprotein 39 (CGP-39), YKL-40, which belongs to the glycosyl hydrolase 18 family. CHI3L1 is present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. CHI3L1 may play a role in defense against pathogens, or in tissue remodeling and also may play an important role in the capacity of cells to respond to and cope with changes in their environment.
Background References:
- Renkema G.H., et al., 1998, Eur. J. Biochem. 251:504-509.
- Houston D.R., et al., 2003, J. Biol. Chem. 278:30206-30212.
Biological Activity:
Measured by the ability of the immobilized protein to support the adhesion of FaDu human squamous cell carcinoma cells. When 50000 cells per well are added to rhCHI3-L1 coated plate, cell adhesion is enhanced in a dose dependent manner. The ED50 for this effect is typically 0. 8 ? 3. 5 μg/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
1116
NCBI Official Name:
chitinase 3-like 1 (cartilage glycoprotein-39)
NCBI Official Symbol:
CHI3L1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
41.0 kDa
Protein Accession #:
AAH38354
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P36222