Cystatin S Recombinant Protein

ProSci
Product Code: PSI-96-208
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-96-208-0.1mg0.1mg£597.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.

Documents

Further Information

Additional Names:
CST4, Cystatin-4, Cystatin-S, Cystatin-S5, Cystatin-SA-III
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Cystatin-4 (CST4) is also known as Cystatin-S, Salivary acidic protein 1, which is a secreted protein, which belongs to the cystatin family. Cystatin-S is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in saliva, tears, urine and seminal fluid. Cystatin-4 / Cystatin S strongly inhibits papain and ficin, partially inhibits stem bromelain and bovine cathepsin C, but does not inhibit porcine cathepsin B or clostripain. Papain is inhibited non-competitively.
Background References:
  • Lamkin M.S., et al., 1991, Arch. Biochem. Biophys. 288:664-670.
  • Ryan C.M., et al., 2010, J. Am. Soc. Mass Spectrom. 21:908-917.
  • Isemura S., et al., 1991, J. Biochem. 110:648-654.
Buffer:
25 mM MES, 150 mM NaCl, pH 6.0
Fusion Tag:
His Tag
NCBI Gene ID #:
1472
NCBI Official Name:
cystatin S
NCBI Official Symbol:
CST4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
15 kDa
Protein Accession #:
AAH65714
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P01036