WFDC2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-389-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
HE4, WAP5, WFDC2, EDDM4
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.
Background References:
- Hellstr?m, Ingegerd, et al., 2003, Cancer Research 63 (13): 3695?3700.
- Kirchhoff C., et al., 1992, Biol Reprod 45 (2): 350?7.
- Schummer M., et al., 1999, Gene 238 (2): 375?85.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
10406
NCBI Official Name:
WAP four-disulfide core domain 2
NCBI Official Symbol:
WFDC2
NCBI Organism:
homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
10.9 kDa
Protein Accession #:
AAH46106
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q14508