PlGF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-625-0.02mg | 0.02mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
PGF, PLGF, PlGF2, PlGF, PGFL, SHGC-10760
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Background References:
- Maglione D., et al., 1993, Oncogene 8 (4): 925?31.
- Khalil A., et al., 2008, PLoS ONE 3 (7): e2766.
- Khurana R., et al., 2005, Circulation 111 (21): 2828?2836.
- Rolny C., et al., 2011, Cancer Cell 19:31-44.
Buffer:
100 mM acetic acid, pH2-3
Fusion Tag:
His Tag
NCBI Gene ID #:
5228
NCBI Official Name:
placental growth factor
NCBI Official Symbol:
PGF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
20.2 kDa
Protein Accession #:
NP_002623.2
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P49763