S100A14 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-667-0.1mg | 0.1mg | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
S100A14, S114, S100A15
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Protein S100-A14 (S100A14) is also known as S100 calcium-binding protein A14 (S114),which belongs to the S-100 family, containing one EF-hand domain.S100A14 is a homodimer can interact with AGER. S100A14 can modulate P53/TP53 protein levels, and play a role in the regulation of cell survival and apoptosis at different concentrations via receptor for advanced glycation end products (RAGE).S100A14 also plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53.
Background References:
- Jin Q., et al., 2011, PLoS ONE 6:E19375-E19375.
- Chen H., et al., 2012, J. Biol. Chem. 287:17109-17119.
- Sapkota D., et al., 2012, Oral Oncol. 48:219-225.
Buffer:
50 mM Tris,150 mM NaCl,pH8.0
Fusion Tag:
His Tag
NCBI Gene ID #:
57402
NCBI Official Name:
S100 calcium binding protein A14
NCBI Official Symbol:
S100A14
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
12.5 kDa
Protein Accession #:
AAH05019
Purity:
>92% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9HCY8