TFPI2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-712-0.05mg | 0.05mg | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
TFPI2, PP5, REF1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Tissue Factor Pathway Inhibitor 2 (TFPI?2) is also known as placental protein 5 (PP5) and retinal pigment epithelial cell factor 1 (REF?1), is a member of the Kunitz-type serine proteinase inhibitor family, is a structural homologue of tissue factor pathway inhibitor (TFPI). TFPI2 is highly abundant in the full-term placenta and widely expressed in umbilical vein endothelial cells, liver, placenta, heart, pancreas, and maternal serum at advanced pregnancy. TFPI?2 may play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa and has no effect on thrombin. Reduced synthesis of TFPI-2 has been related to numerous pathophysiological processes such as inflammation, angiogenesis, atherosclerosis, retinal degeneration and tumor growth / metastasis.
Background References:
- Rao C.N., et al., 1995, Arch. Biochem. Biophys. 317:311-314.
- Tanaka Y.,?et?al., 2004, Invest.?Ophthalmol.?Vis.?Sci.?45:245.??
- Rollin J.,?et?al.,?2005,?Br,?J.?Cancer?92:775.?
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
7980
NCBI Official Name:
tissue factor pathway inhibitor 2
NCBI Official Symbol:
TFPI2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
22.7 kDa
Protein Accession #:
NP_006519.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P48307