VSIG4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-780-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
VSIG4, CRIg, Z39IG
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
V-set and immunoglobulin domain-containing protein 4 (VSIG4) is also known as Protein Z39Ig, is a type I transmembrane glycoprotein. VSIG4 is a B7 family-related protein and an Ig superfamily member. VSIG4 contains two Ig-like (immunoglobulin-like) domains. VSIG4 is abundantly expressed in several fetal tissues. In adult tissues, the highest expression of VSIG4 is in lung and placenta. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. VSIG4 is a phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production.
Background References:
- Vogt L., et al., 2006, J. Clin. Invest. 116:2817-2826.
- Wiesmann C., et al., 2006, Nature 444:217-220.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
11326
NCBI Official Name:
V-set and immunoglobulin domain containing 4
NCBI Official Symbol:
VSIG4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
30 kDa
Protein Accession #:
AAH10525
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9Y279