ANGPTL4 (166-406) Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-028-0.1mg | 0.1mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
ANGPTL4, ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, Angiopoietin like 4
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
Background References:
- Yoon J.C., et al., 2000, Mol. Cell. Biol. 20:5343-5349.
- Ito Y., et al., 2003, Cancer Res. 63:6651-6657.
- Zhu H., et al., 2002, Zhonghua Zhong Liu Za Zhi 24:123-125.
Buffer:
50 mM MOPS, 100 mM NaCl, pH7.2 with 0.1% CHAPS
Fusion Tag:
N-His Tag
NCBI Gene ID #:
51129
NCBI Official Name:
angiopoietin-like 4
NCBI Official Symbol:
ANGPTL4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
27.9 kDa
Protein Accession #:
NP_647475
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9BY76