IL13RA1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-96-431-0.2mg | 0.2mg | £560.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Storage:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL13RA1, CD213A1, IL-13Ra, NR4, RP13-128O4.2, IL13Rα1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Background References:
- Caput, D. et al., 1996, J. Biol. Chem. 271:16921.
- Donaldson, D.D. et al., 1998, J. Immunol. 161:2317.
- Hilton, D.J. et al., 1996, Proc. Natl. Acad. Sci. USA 93:497.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
C-Fc Tag
NCBI Gene ID #:
16164
NCBI Official Name:
interleukin 13 receptor, alpha 1
NCBI Official Symbol:
Il13ra1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
62.7 kDa
Protein Accession #:
NP_598751
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O09030