IL-38 (human) Matched Pair Detection Set
| Code | Size | Price |
|---|
| AG-46B-0007-KI01 | 1 Set | £570.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
Blue Ice
Storage:
-20°C
Further Information
Alternate Names/Synonyms:
Interleukin-1 Family Member 10 theta; IL-1F10; FIL1theta; FKSG75; IL-1HY2; IL1-theta; Interleukin-1 HY2; Interleukin-1 Receptor Antagonist FKSG75
Assay Type:
Sandwich
Detection Type:
Colorimetric
EClass:
32160000
Handling Advice:
Avoid freeze/thaw cycles.
Kit Contains:
1 vial standard protein (1µg) (lyophilized) [STD] | 1 vial coating antibody (270µl) [COAT] | 1 vial detection antibody (60µl) [DET] | 1 vial anti-IgG-HRP (10µg) (lyophilized) [HRP]
Long Description:
Matched Pair Detection Set. Recognizes human IL-38. Colorimetric assay. Sample Type: Cell Culture Supernatant, Serum. Range: 0.031 to 2ng/ml. Sensitivity: 20pg/ml. IL-38 (also called IL-1F10, and previously named IL1HY2, FIL1theta, or IL-1theta) is expressed in skin, tonsil, thymus, spleen, fetal liver, and salivary glands. The expression in a variety of immune tissues and similarity to IL-36Ra and IL-1Ra suggest a role of IL-38 in the inflammatory response. IL-38 binds to the IL-36R and exerts antagonistic effects similar to those of IL-36Ra.
NCBI, Uniprot Number:
Q8WWZ1
Package Type:
Box
Product Description:
IL-38 (also called IL-1F10, and previously named IL1HY2, FIL1theta, or IL-1theta) is expressed in skin, tonsil, thymus, spleen, fetal liver, and salivary glands. The expression in a variety of immune tissues and similarity to IL-36Ra and IL-1Ra suggest a role of IL-38 in the inflammatory response. IL-38 binds to the IL-36R and exerts antagonistic effects similar to those of IL-36Ra.
Range:
0.031 to 2ng/ml
Sample Type:
Cell Culture Supernatant, Serum
Sensitivity:
20pg/ml
Specificity:
Recognizes human IL-38.
Transportation:
Non-hazardous
UNSPSC Category:
ELISA Kits
UNSPSC Number:
41116126
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.
References
Interleukin-38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus: I. Rudloff, et al.; Arthr. Rheumatol. 67, 3219 (2015) | Elevated plasma IL-38 concentrations in patients with acute ST-segment elevation myocardial infarction and their dynamics after reperfusion treatment: Y. Zhong, et al.; Med. Inflamm. 2015, ID490120 (2015) | Aberrant expression of novel cytokine IL-38 and regulatory T lymphocytes in childhood asthma: M. Chu, et al.; Molecules 21, E933 (2016) | Plasma interleukin-38 in patients with rheumatoid arthritis: W.D. Xu, et al.; Int. Immunopharmacol. 65, 1 (2018) | Reduced interleukin-38 in non-small cell lung cancer is associated with tumour progression: F. Wang, et al.; Open Biol. 8, 180132 (2018) | Interleukin-38 increases the insulin sensitivity in children with the type 2 diabetes: Y. Liu, et al.; Int. Immunopharm. 82, 106264 (2020)