1-(4'-Carboxybutyl)-3,7-dimethylxanthine
| Code | Size | Price |
|---|
| CDX-C0312-M010 | 10 mg | £121.00 |
Quantity:
| CDX-C0312-M025 | 25 mg | £230.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
2,3,6,7-Tetrahydro-3,7-dimethyl-2,6-dioxo-1H-purine-1-pentanoic acid DB-dmx
Appearance:
White powder.
CAS:
38975-44-9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C12H16N4O4/c1-14-7-13-10-9(14)11(19)16(12(20)15(10)2)6-4-3-5-8(17)18/h7H,3-6H2,1-2H3,(H,17,18)
InChiKey:
JDMFPLGXRUJOTC-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 38975-44-9. Formula: C12H16N4O4. MW: 280.28. Synthetic Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-alpha cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the beta-2 integrin CD11b/CD18.
MDL:
MFCD09264519
Molecular Formula:
C12H16N4O4
Molecular Weight:
280.28
Package Type:
Vial
Precautions:
P264, P270, P301, P312, P330
Product Description:
Pentoxifylline (PTX) metabolite. Can be used as reference material. Showed platelet aggregation in whole blood in vitro. Shown to be more effective than PTX in protecting WC/1 murine fibrosarcoma cells from TNF-alpha cytotoxicity and in inhibiting neutrophil superoxide anion production, degranulation (lactoferrin release) and surface expression of the beta-2 integrin CD11b/CD18.
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
CN1C=NC2=C1C(=O)N(CCCCC(O)=O)C(=O)N2C
Solubility Chemicals:
Soluble in ethyl acetate.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) S. Hayashi, et al.; Chem. Pharm. Bull. 24, 1384 (1976) | (2) T.A. Bryce, et al.; J. Chromatogr. 344, 397 (1985) | (3) G.W. Sullivan, et al.; Infect. Immun. 56, 1722 (1988) | (4) M. Fantin, et al.; Eur. J. Pharmacol. 301, 535 (2006) | (5) M. Magnusson, et al.; Eur. J. Pharmacol. 290, 581 (2008)
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