2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt hydrate
| Code | Size | Price |
|---|
| CDX-M0096-M001 | 1 mg | £59.00 |
Quantity:
| CDX-M0096-M005 | 5 mg | £205.00 |
Quantity:
| CDX-M0096-M025 | 25 mg | £694.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
4-MUNANA; 4-Methylumbelliferyl-N-acetyl-alpha-D-neuraminic acid sodium salt hydrate; Neu5Ac-alpha-4MU; 4MU-NeuNAc
Appearance:
Light yellow powder.
CAS:
76204-02-9 (anhydrous)
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C21H25NO11.Na.H2O/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);;1H2/q;+1;/p-1/t13-,14+,17+,18+,19+,21?;;/m0./s1
InChiKey:
NSQMRVBWXQQIKF-HCNBQXOJSA-M
Long Description:
Chemical. CAS: 76204-02-9 (anhydrous). Formula: C21H24NNaO11 . xH2O. MW: 489.41 (anhydrous basis). Synthetic Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm (after cleavage by neuraminidase). Used for fluorescent staining of sialidases in PAGE.
MDL:
MFCD00057309
Molecular Formula:
C21H24NNaO11 . xH2O
Molecular Weight:
489.41 (anhydrous basis)
Package Type:
Vial
Product Description:
Fluorogenic substrate used to measure sensitively enzymatic neuraminidase activity in fluorometric assays in mammalian and viral sources. Neuraminidase is catalyzed by the hydrolysation to form N-acetylneuraminic acid and the blue fluorescent soluble compound 4-Methylumbelliferone, which can be detected fluorometrically. Spectral data: lambdaex 315 nm| lambdaem 374 nm (pH.7.0) or lambdaex 365 nm| lambdaem 445 nm (after cleavage by neuraminidase). Used for fluorescent staining of sialidases in PAGE.
Purity:
>95% (NMR)
SMILES:
O.CC(=O)N[C@@H]1[C@H](O)C[C@@](OC2=CC3=C(C=C2)C(C)=CC(=O)O3)(OC1[C@H](O)[C@H](O)CO)C(=O)O[Na]
Solubility Chemicals:
Soluble in water or methanol.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) M. Potier, et al.; Anal. Biochem. 94, 287 (1979) | (2) R.W. Myers, et al.; Anal. Biochem. 101, 166 (1980) | (3) S. Matsuzaki, et al.; Jpn. J. Med. 23, 123 (1987) | (4) E. Monti, et al.; Glycobiol. 9, 1313 (1999) | (5) N.T. Wetherall, et al.; J. Clin. Microbiol. 41, 742 (2003) |(6) D.P. Nayak & U. Reichl; J. Virol. Meth. 122, 9 (2004) | (7) H.L. Yen, et al.; J. Virol. 80, 8787 (2006) | (8) H. Zhi, et al.; J. Spectrosc. 2013, 1 (2014)
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