Sulfamethoxazole hydroxylamine

Chemodex
Product Code: CDX-S0056
Supplier: Chemodex
CodeSizePrice
CDX-S0056-M01010 mg£205.00
Quantity:
CDX-S0056-M02525 mg£401.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
Sulfamethoxazole N4-hydroxylamine; SMX-HA; SMX-NHOH; NSC 665547; 4-(Hydroxyamino)-N-(5-methyl-3-isoxazolyl)benzenesulfonamide
Appearance:
Off-white powder.
CAS:
114438-33-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H315, H317, H319, H335
InChi:
InChI=1S/C10H11N3O4S/c1-7-6-10(12-17-7)13-18(15,16)9-4-2-8(11-14)3-5-9/h2-6,11,14H,1H3,(H,12,13)
InChiKey:
MJAMPGKHIZXVFJ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 114438-33-4. Formula: C10H11N3O4S. MW: 269.28. Synthetic Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to induce lymphocyte toxicity and suppression of proliferation. Compound can be used as analytical reference material.
MDL:
MFCD00870463
Molecular Formula:
C10H11N3O4S
Molecular Weight:
269.28
Package Type:
Vial
Precautions:
P261, P280, P305, P351, P338
Product Description:
Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to induce lymphocyte toxicity and suppression of proliferation. Compound can be used as analytical reference material.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
CC1=CC(NS(=O)(=O)C2=CC=C(NO)C=C2)=NO1
Solubility Chemicals:
Soluble in methanol or DMSO. Sligthly soluble in water.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) J.S. Leeder, et al.; Biochem. Pharmacol. 41, 575 (1991) | (2) A.E. Cribb & S.P. Spielberg; Clin. Pharmacol. Ther. 51, 522 (1992) | (3) M.J. Rieder, et al.; Int. J. Immunopharmacol. 14, 1175 (1992) | (4) D.A. Hess, et al.; J. Pharmacol. Exp. Ther. 281, 540 (1997) | (5) D.A. Hess, et al.; FASEB J. 13, 1688 (1999) | (6) D.A. Hess, et al.; FASEB J. 15, 1855 (2001)