Artemisinin
Product Code: AG-CN2-0467
Product Group: Natural Products and Extracts
Supplier: AdipoGen Life Sciences
| Code | Size | Price |
|---|
| AG-CN2-0467-M100 | 100 mg | £45.00 |
Quantity:
| AG-CN2-0467-M500 | 500 mg | £90.00 |
Quantity:
| AG-CN2-0467-G001 | 1 g | £170.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
Qinghaosu; Arteannuin
Appearance:
White solid.
CAS:
63968-64-9
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.Protect from moisture and oxygen.
InChi:
InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChiKey:
BLUAFEHZUWYNDE-NNWCWBAJSA-N
Long Description:
Chemical. CAS: 63968-64-9. Formula: C15H22O5. MW: 282.3. Isolated from Artemisia annua. Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).
MDL:
MFCD00081057
Molecular Formula:
C15H22O5
Molecular Weight:
282.3
Package Type:
Vial
Product Description:
Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Functional ARX inhibitor. Enhancer of GABAA signaling. Shown to promote the in vivo conversion of pancreatic alpha cells into functional beta-like cells through enhanced GABA signaling and may have potential as a therapeutic for diabetes. Targets Gephyrin.
Purity:
>98% (HPLC)
SMILES:
[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(OC(=O)[C@@H]2C)O4
Solubility Chemicals:
Soluble in DMSO or ethanol.
Source / Host:
Isolated from Artemisia annua.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
References
Qinghaosu (artemisinin): an antimalarial drug from China: D.L. Klayman; Science 228, 1049 (1985) | The development of the antimalarial drugs with new type of chemical structure--qinghaosu and dihydroqinghaosu: Y. Tu; SE Asian J. Trop. Med. Publ. Health 35, 250 (2004) | Artemisinin induces apoptosis in human cancer cells: N.P. Singh & H.C. Lai; Anticancer Res. 24, 2277 (2004) | Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-kappaB pathway in microglia cells: C. Zhu, et al.; PLoS One 7, e35125 (2012) | Differential effect of artemisinin against cancer cell lines: M. Tilaoui, et al.; Nat. Prod. Bioprospect. 4, 189 (2014) | Artemisinins target GABAA receptor signaling and impair alpha cell identity: J. Li, et al.; Cell 168, 86 (2017)
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