CD74 (mouse):Fc (mouse) (rec.)
| Code | Size | Price |
|---|
| CHI-MF-110CD74-C100 | 100 ug | £385.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Application: Activity Assay
Shipping:
BI
Storage:
+4°C(Short Term) -20°C(Long Term)
Documents
Further Information
Alternate Names/Synonyms:
CLIP; DHLAG; HLADG
EClass:
32160000
Endotoxin:
<5EU/mg protein (LAL test; Lonza).
Form (Short):
solid
Formulation:
Lyophilized from 0.2µm-filtered solution in PBS.
Handling Advice:
Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. The extracellular domain of mouse CD74 (aa 56-215) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: HEK 293 cells. Endotoxin content: <5EU/mg protein (LAL test; Lonza). Lyophilized from 0.2µm-filtered solution in PBS. Purity: >98% (SDS-PAGE). CD74 is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. The cytoplasmic portion of CD74 can be released by intramembrane cleavage to activate NFkB. CD74 is upregulated in several cancers and is also expressed by non-immune cells during inflammation.
Molecular Weight:
~55kDa (SDS-PAGE)
NCBI, Uniprot Number:
NP_034675.1
Package Type:
Plastic Vial
Product Description:
CD74 is a transmembrane protein which, on antigen presenting cells, is the invariant chain that chaperones MHC class II dimers from the endoplasmic reticulum to the cell surface. The cytoplasmic portion of CD74 can be released by intramembrane cleavage to activate NFkB. CD74 is upregulated in several cancers and is also expressed by non-immune cells during inflammation.
Purity:
>98% (SDS-PAGE)
Sequence:
The extracellular domain of mouse CD74 (aa 56-215) is fused to the N-terminus of the Fc region of mouse IgG2a.
Source / Host:
HEK 293 cells
TAGs:
Fc
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.