TDP1 Antibody

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ProSci
Product Code: PSI-43-543
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-543-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-543 (2ug/ml) staining of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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43-543 (2ug/ml) staining of Jurkat nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
TDP1, tyrosyl-DNA phosphodiesterase 1, FLJ11090, MGC104252
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 75kDa band observed in nuclear lysates of cell line Jurkat (calculated MW of 68.4kDa according to NP_060789.2). Recommended concentration: 1-3ug/ml.
Background References:
  • Antony S, Marchand C, Stephen AG, Thibaut L, Agama KK, Fisher RJ, Pommier YNovel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-PNDGTAQRTENHG
NCBI Gene ID #:
55775
NCBI Official Name:
tyrosyl-DNA phosphodiesterase 1
NCBI Official Symbol:
TDP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 75kDa
Protein Accession #:
NP_060789.2
Protein GI Number:
37999797
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience, Signal Transduction
SPECIFICITY:
Reported variants represent identical protein: NP_001008744.1, NP_060789.2
Swissprot #:
Q9NUW8