OAS2 Antibody

ProSci
Product Code: PSI-43-531
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-531-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-531 (0.3ug/ml) staining of Daudi (A), Jurkat (B) and K562 (C) lysates (35ug protein in RIPA buffer). Detected by chemiluminescence.
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43-531 (0.3ug/ml) staining of Daudi (A), Jurkat (B) and K562 (C) lysates (35ug protein in RIPA buffer). Detected by chemiluminescence.

Further Information

Additional Names:
OAS2, 2'-5'-oligoadenylate synthetase 2, 69/71kDa, (2'-5')oligo(A) synthetase 2, 2'-5'-oligoadenylate synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 70kDa band observed in lysates of cell lines Daudi, Jurkat and K562 (calculated MW of 78.8kDa according to NP_002526.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Lin et al, J Immunol. 2009 Dec 15;183(12):8035-43. PMID: 19923450). Recommended concentration: 0.3-1ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Breast. Recommended concentration: 5ug/ml.
Background References:
  • Dugan JW, Albor A, David L, Fowlkes J, Blackledge MT, Martin TM, Planck SR, Rosenzweig HL, Rosenbaum JT, Davey MP.Nucleotide oligomerization domain-2 interacts with 2'-5'-oligoadenylate synthetase type 2 and enhances RNase-L function in THP-1 cells.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: QPNKCFLEQIDSAVN
NCBI Gene ID #:
4939
NCBI Official Name:
2'-5'-oligoadenylate synthetase 2
NCBI Official Symbol:
OAS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 70kDa
Protein Accession #:
NP_058197.2, NP_002526.2
Protein GI Number:
74229019
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience
SPECIFICITY:
This antibody is expected to recognize reported isoform 1 (NP_058197.2) and isoform 2 (NP_002526.2).
Swissprot #:
P29728