CX3CR1 Antibody

ProSci
Product Code: PSI-43-638
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-638-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-638 (2ug/ml) staining of Kelly (A) and U251-MG (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

43-638 (2ug/ml) staining of Kelly (A) and U251-MG (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
CX3CR1, chemokine (C-X3-C motif) receptor 1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, C-X3-C CKR-1, CMK-BRL-1, CMK-BRL1, CX3C chemokine receptor 1, G protein-coupled receptor 13, G-protein coupled receptor 13, beta chemokine receptor-like 1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 39kDa band observed in lysates of cell line Kelly and 37kDa in lysates of cell line U251-MG (calculated MW of 40.4kDa according to NP_001328.1). Recommended concentration: 1-3ug/ml.
Background References:
  • Marchesi F, Piemonti L, Fedele G, Destro A, Roncalli M, Albarello L, Doglioni C, Anselmo A, Doni A, Bianchi P, Laghi L, Malesci A, Cervo L, Malosio M, Reni M, Zerbi A, Di Carlo V, Mantovani A, Allavena P.The chemokine receptor CX3CR1 is involved in the neural tropism and malignant behavior of pancreatic ductal adenocarcinoma.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-DQFPESVTENFEYD
NCBI Gene ID #:
1524
NCBI Official Name:
chemokine (C-X3-C motif) receptor 1
NCBI Official Symbol:
CX3CR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 39kDa
Protein Accession #:
NP_001164645.1, NP_001328.1
Protein GI Number:
4503171
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer,Chemokines & Cytokines,Infectious Disease,Cancer Chemokine Infectious Disease
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_001164645.1; NP_001328.1). Reported variants represent identical protein: NP_001164643.1, NP_001328.1, NP_001164642.1.
Swissprot #:
P49238