Lamin B1 Antibody
| Code | Size | Price |
|---|
| PSI-43-160-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
LMNB1, lamin B1, ADLD, LMN, LMN2, LMNB, MGC111419, OTTHUMP00000159218, lamin-B1
Application Note:
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 70kDa band observed in nuclear lysates of cell lines HeLa and Jurkat and approx. 70-75kDa in Mouse Liver lysates (calculated MW of 66.4kDa according to Human NP_005564.1 and 66.8kDa according to Mouse NP_034851.2) Recommended concentration: 1-3ug/ml.
Background References:
- Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N.Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-DVKVILKNSQGE
NCBI Gene ID #:
4001
NCBI Official Name:
lamin B1
NCBI Official Symbol:
LMNB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 70kDa
Protein Accession #:
NP_005564.1, NP_001185486.1
Protein GI Number:
125953
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience, Obesity, Signal Transduction
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_005564.1; NP_001185486.1).
Swissprot #:
P20700