UNC5B Antibody

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ProSci
Product Code: PSI-43-468
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-468-0.1mg0.1mg£626.00
Quantity:
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Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-468 (2ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
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43-468 (2ug/ml) staining of Human Bone Marrow lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunizing peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
UNC5B, unc-5 homolog B (C. elegans), UNC5H2, p53RDL1, netrin receptor UNC5B, p53-regulated receptor for death and life protein 1, protein unc-5 homolog 2, protein unc-5 homolog B, transmembrane receptor Unc5H2, unc-5 homolog 2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Approx 90kDa band observed in Human Bone Marrow lysates (calculated MW of 104kDa according to NP_734465.2). Some minor background is detected and is blocked by the immunizing peptide. We call for caution when used for other assays than Western blot. Recommended concentration: 1-3ug/ml.
Background References:
  • Tang X, Jang SW, Okada M, Chan CB, Feng Y, Liu Y, Luo SW, Hong Y, Rama N, Xiong WC, Mehlen P, Ye K.Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: C-SARDWIFQLKTQAHQ
NCBI Gene ID #:
219699
NCBI Official Name:
unc-5 homolog B (C. elegans)
NCBI Official Symbol:
UNC5B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 90kDa
Protein Accession #:
NP_734465.2
Protein GI Number:
85861262
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Other
Swissprot #:
Q8IZJ1