NPC1 Antibody

ProSci
Product Code: PSI-43-348
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-348-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-348 (0.5ug/ml) staining of HEK293 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

43-348 (0.5ug/ml) staining of HEK293 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
NPC1, Niemann-Pick disease, type C1, FLJ98532, NPC
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 170kDa band observed in lysates of cell line HEK293 (calculated MW of 142kDa according to NP_000262.2). Recommended concentration: 0.5-1.5ug/ml.
Background References:
  • Tang Y, Leao IC, Coleman EM, Broughton RS, Hildreth JE, Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-TYHTVLQTSADFID
NCBI Gene ID #:
4864
NCBI Official Name:
Niemann-Pick disease, type C1
NCBI Official Symbol:
NPC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 170kDa
Protein Accession #:
NP_000262.2
Protein GI Number:
255652944
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Obesity,Obesity
Swissprot #:
O15118