IL-17B Antibody

ProSci
Product Code: PSI-43-345
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-345-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-345 (2ug/ml) staining of Human Ileum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

43-345 (2ug/ml) staining of Human Ileum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
IL17B, interleukin 17B, IL-17B, IL-20, NIRF, ZCYTO7, cytokine Zcyto7, cytokine-like protein ZCYTO7, interleukin 20, interleukin-17 beta, interleukin-17B, interleukin-20, neuronal interleukin-17 related factor, neuronal interleukin-17-related factor
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 20kDa band observed in Human Ileum lysates (calculated MW of 20.4kDa according to NP_055258.1). Recommended concentration: 1-3ug/ml. An additional band of unknown identity was also consistently observed at 17kDa. This band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any such results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K.IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: SELAQRKCEVNLQ
NCBI Gene ID #:
27190
NCBI Official Name:
interleukin 17B
NCBI Official Symbol:
IL17B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 20kDa
Protein Accession #:
NP_055258.1
Protein GI Number:
20143877
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Chemokines & Cytokines,Immunology,Cytokine Immunology
Swissprot #:
Q9UHF5