SCARB1 / SR-BI Antibody

ProSci
Product Code: PSI-43-585
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-585-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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43-585 (0.01ug/ml) staining of Human Adrenal Gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

43-585 (0.01ug/ml) staining of Human Adrenal Gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
SCARB1, scavenger receptor class B, member 1, CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1, CD36 and LIMPII analogous 1, CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1, scavenger receptor class B member 1, scavenger receptor class B type III
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 85kDa band observed in Human Adrenal gland lysates (calculated MW of 57.0kDa according to NP_005496.4). We do note that SCARB1 is a glycoprotein which makes a higher size band to be expected, and this is consistent with observations with different antibodies from other commercial sources. Recommended concentration: 0.01-0.03ug/ml.
Background References:
  • Zhang QH, Zu XY, Cao RX, Liu JH, Mo ZC, Zeng Y, Li YB, Xiong SL, Liu X, Liao DF, Yi GH.An involvement of SR-B1 mediated PI3K-Akt-eNOS signaling in HDL-induced cyclooxygenase 2 expression and prostacyclin production in endothelial cells.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-TSAPKGSVLQEAK
NCBI Gene ID #:
949
NCBI Official Name:
scavenger receptor class B, member 1
NCBI Official Symbol:
SCARB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 85kDa
Protein Accession #:
NP_005496.4
Protein GI Number:
37999904
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Infectious Disease,Infectious Disease
SPECIFICITY:
This antibody is expected to recognize isoform 1 (NP_005496.4) only.
Swissprot #:
Q8WTV0