PSMC5 Antibody
| Code | Size | Price |
|---|
| PSI-28-816-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- C. Elegans
- Canine (dog)
- Drosophila (fruit fly)
- Human
- Mouse
- Rat
- Zebrafish
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PSMC5 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Documents
Further Information
Additional Names:
PSMC5, S8, p45, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Application Note:
PSMC5 antibody can be used for detection of PSMC5 by ELISA at 1:312500. PSMC5 antibody can be used for detection of PSMC5 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Background References:
- Inoue, T., et al., (2006) Biochem. Biophys. Res. Commun. 342 (3), 829-834.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC5.
NCBI Gene ID #:
5705
NCBI Official Name:
proteasome (prosome, macropain) 26S subunit, ATPase, 5
NCBI Official Symbol:
PSMC5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
NP_002796
Protein GI Number:
24497435
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
P62195
User NOte:
Optimal dilutions for each application to be determined by the researcher.