Glycine receptor, alpha 1 Antibody
| Code | Size | Price |
|---|
| PSI-43-226-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
Glra1, glycine receptor, alpha 1, GLYRA1, glycine receptor 48 kDa subunit, glycine receptor strychnine-binding subunit, glycine receptor subunit alpha-1, glycine receptor, alpha 1 subunit
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 60kDa band observed in Mouse and Rat Testis lysates (calculated MW of 51.7kDa according to Mouse NP_065238.2). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0.3-1ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Lung and Kidney. Recommended concentration: 5ug/ml.
Background References:
- Wang Q, Lynch JW.Activation and desensitization induce distinct conformational changes at the extracellular-transmembrane domain interface of the glycine receptor.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
Immunogen:
The immunogen for this antibody is: CLQAKDGISVKGAN
NCBI Gene ID #:
2741
NCBI Official Name:
glycine receptor, alpha 1
NCBI Official Symbol:
Glra1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 60kDa
Protein Accession #:
NP_037265.1
Protein GI Number:
119372310
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Neuroscience,Signal Transduction,Neuroscience Signal Transduction Membrane Membrane
SPECIFICITY:
The immunizing peptide represents part of the cytoplasmic domain. The antibody is not expected to cross-react with other glycine receptor alpha proteins.
Swissprot #:
P23415