ATRX Antibody
| Code | Size | Price |
|---|
| PSI-43-530-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
ATRX, alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae), RP5-875J14.1, ATR2, MGC2094, MRXS3, RAD54, RAD54L, SHS, XH2, XNP, ZNF-HX , DNA dependent ATPase and helicase, OTTHUMP00000062079, RAD54 (Saccharomyces cerevisiae), X-linked nuclear protein, Zinc finger helicase, alpha thalassemia/mental retardation syndrome X-linked (RAD54 (S. cerevisiae) homolog), helicase 2, X-linked, transcriptional regulator ATRX
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the expected size of 300kDa according to the literature (PMID: 15591283). Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
- Abidi FE, Cardoso C, Lossi AM, Lowry RB, Depetris D, Mattei MG, Lubs HA, Stevenson RE, Fontes M, Chudley AE, Schwartz CE. Mutation in the 5' alternatively spliced region of the XNP/ATR-X gene causes Chudley-Lowry syndrome.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Dog
Immunogen:
The immunogen for this antibody is: C-KKDQSDETSEDDKKQ
NCBI Gene ID #:
546
NCBI Official Name:
alpha thalassemia/mental retardation syndrome X-linked
NCBI Official Symbol:
ATRX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000480.2, NP_612114.1, NP_612115.1
Protein GI Number:
311033500
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction,Signal Transduction
SPECIFICITY:
This antibody is expected to recognise all three reported isoforms (NP_000480.2, NP_612114.1, NP_612115.1).
Swissprot #:
P46100