Il6ra Antibody

ProSci
Product Code: PSI-43-423
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-423-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
Il6ra, interleukin 6 receptor, alpha, CD126, IL-6R, Il6r, MGC30256, IL-6 receptor alpha chain, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6R
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments in Mouse Spleen and Thymus lysates and in lysates of cell lines NIH3T3 and NSO gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • Boulanger MJ, Chow DC, Brevnova EE, Garcia KC.Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat
Immunogen:
The immunogen for this antibody is: C-YLLQFQLRYRPVWSK
NCBI Gene ID #:
16194
NCBI Official Name:
interleukin 6 receptor, alpha
NCBI Official Symbol:
Il6ra
NCBI Organism:
Mus musculus?
Physical State:
Liquid
Protein Accession #:
NP_034689.2
Protein GI Number:
110431356
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction
SPECIFICITY:
This antibody is expected to recognize all reported isoforms (NP_000556.1; NP_852004.1). The sequence of the immunizing peptide corresponds with a part of the extracellular domain.
Swissprot #:
P22272