Chrne Antibody

ProSci
Product Code: PSI-43-161
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-43-161-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
Chrne, cholinergic receptor, nicotinic, epsilon, DN-183N8.9, Acre, AChrepsilon, AchR epsilon subunit, OTTMUSP00000006330, acetylcholine receptor epsilon subunit, acetylcholine receptor subunit epsilon
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Preliminary experiments in Mouse and Rat Heart, Skeletal Muscle and Testis lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Background References:
  • Faber CG, Molenaar PC, Vles JS, Bonifati DM, Verschuuren JJ, van Doorn PA, Kuks JB, Wokke JH, Beeson D, De Baets M.AChR deficiency due to epsilon-subunit mutations: two common mutations in the Netherlands.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat
Immunogen:
The immunogen for this antibody is: C-DGNTINKIDIDT
NCBI Gene ID #:
11448
NCBI Official Name:
cholinergic receptor, nicotinic, epsilon polypeptide
NCBI Official Symbol:
Chrne
NCBI Organism:
Homo Sapiens
Physical State:
Liquid
Protein Accession #:
NP_033733.1
Protein GI Number:
6752950
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Signal Transduction, Stem Cell
SPECIFICITY:
The immunizing peptide represents a part of an extracellular domain
Swissprot #:
P20782