Gabra6 Antibody
| Code | Size | Price |
|---|
| PSI-43-340-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
Gabra6, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6, RP23-288I22.1, Gabra-6, alpha6, GABA(A) receptor subunit alpha-6, OTTMUSP00000006689, gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6, gamma-aminobutyric acid A recptor, subunit alpha 6, gamma-aminobutyric acid receptor subunit alpha-6, subunit alpha 6 gamma-aminobutyric acid (GABA-A) receptor
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 75kDa band in Mouse fetal Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 49.8kDa according to NP_032094.2. The 75kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
- Green EK, Grozeva D, Moskvina V, Hamshere ML, Jones IR, Jones L, Forty L, Caesar S, Gordon-Smith K, Fraser C, Russell E, St Clair D, Young AH, Ferrier N, Farmer A, McGuffin P, Holmans PA, Owen MJ, O'Donovan MC, Craddock N.Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-PATGGTSKIDQYSR
NCBI Gene ID #:
2559
NCBI Official Name:
gamma-aminobutyric acid (GABA) A receptor, alpha 6
NCBI Official Symbol:
Gabra6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001093111.1, NP_032094.2
Protein GI Number:
153792343
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer,Obesity,Signal Transduction,
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_001093111.1; NP_032094.2).
Swissprot #:
Q16445