Thiocolchicoside
| Code | Size | Price |
|---|
| CDX-T0175-M025 | 25 mg | £205.00 |
Quantity:
| CDX-T0175-M100 | 100 mg | £596.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
BRN0072205; NSC147755; Coltramyl; 10-thio-Colchicoside; 2-Demethoxy-2-glucosidoxythiocolchicine
Appearance:
Light yellow to dark yellow powder.
CAS:
602-41-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H302, H317, H335
InChi:
InChI=1S/C27H33NO10S/c1-12(30)28-16-7-5-13-9-18(37-27-24(34)23(33)22(32)19(11-29)38-27)25(35-2)26(36-3)21(13)14-6-8-20(39-4)17(31)10-15(14)16/h6,8-10,16,19,22-24,27,29,32-34H,5,7,11H2,1-4H3,(H,28,30)/t16-,19+,22+,23-,24+,27+/m0/s1
InChiKey:
LEQAKWQJCITZNK-AXHKHJLKSA-N
Long Description:
Chemical. CAS: 602-41-5. Formula: C27H33NO10S. MW: 563.6. Synthetic. Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Described to be a muscle relaxant. Anti-inflammatory agent with analgesic properties. Shown to be an anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Therapeutic option for the management of bone metastatic disease.
MDL:
MFCD09026931
Molecular Formula:
C27H33NO10S
Molecular Weight:
563.6
Package Type:
Vial
Precautions:
P301, P312, P302, P352, P304, P340, P330
Product Description:
Potent competitive gamma-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist. Described to be a muscle relaxant. Anti-inflammatory agent with analgesic properties. Shown to be an anticancer compound through inhibition of NF-kappaB and NF-kappaB-regulated gene products. Therapeutic option for the management of bone metastatic disease.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
COC1=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C=C2CC[C@H](NC(C)=O)C3=CC(=O)C(SC)=CC=C3C2=C1OC
Solubility Chemicals:
Soluble in water (10 mg/ml).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) J.M. Janbroers; Acta Ther. 13, 221 (1987) | (2) M. Carta, et al.; Neuropharmacology 51, 805 (2006) | (3) S. Reuter, et al.; Cancer Prev. Res. 3, 1462 (2010) | (4) O. Micheau, et al.; Br. J. Pharmacol. 165, 2124 (2012)
Related Products
| Product Name | Product Code | Supplier |
|---|