ZnAF-1F DA Solution
| Code | Size | Price |
|---|
| CDX-Z0511-M001 | 1 mg | £487.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
5-({2-[Bis(2-pyridinylmethyl)amino]ethyl}amino)-2-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid diacetate
Appearance:
Liquid.
Concentration:
5mM in DMSO (1mg in 0.29ml DMSO)
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light.
InChi:
InChI=1S/C38H30F2N4O7/c1-22(45)48-35-18-33-29(16-31(35)39)38(30-17-32(40)36(49-23(2)46)19-34(30)50-33)28-10-9-24(15-27(28)37(47)51-38)43-13-14-44(20-25-7-3-5-11-41-25)21-26-8-4-6-12-42-26/h3-12,15-19,43H,13-14,20-21H2,1-2H3
InChiKey:
LPSDYSDKFVFVIH-UHFFFAOYSA-N
Long Description:
Chemical. Formula: C38H30F2N4O7. MW: 692.66. Synthetic. For application to living cells, the diacetyl derivative of ZnAF-1F, ZnAF-1F DA, was synthesized. ZnAF-1F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-1F, which is retained in the cells. ZnAF-1F DA has been used to measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices. Spectral data: lambdaex 492nm; lambdaem 514nm in PBS.
Molecular Formula:
C38H30F2N4O7
Molecular Weight:
692.66
Package Type:
Vial
Product Description:
For application to living cells, the diacetyl derivative of ZnAF-1F, ZnAF-1F DA, was synthesized. ZnAF-1F DA can permeate through the cell membrane, and is hydrolyzed by esterase in the cytosol to yield ZnAF-1F, which is retained in the cells. ZnAF-1F DA has been used to measure the changes of intracellular Zn2+ in cultured cells and hippocampal slices. Spectral data: lambdaex 492nm; lambdaem 514nm in PBS.
Purity:
>95% (HPCE)
SMILES:
CC(=O)OC1=CC2=C(C=C1F)C1(OC(=O)C3=C1C=CC(NCCN(CC1=CC=CC=N1)CC1=NC=CC=C1)=C3)C1=CC(F)=C(OC(C)=O)C=C1O2
Solubility Chemicals:
Soluble in DMSO.
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) S. Ueno, et al.; J. Cell Biol. 158, 215 (2002) | (2) T. Hirano, et al.; JACS 124, 6555 (2002)