Jagged-1 Antibody [J1G53-3]

Contact us
ProSci
Product Code: PSI-36-051
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-36-051-100ug100ug£524.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: J1G53-3
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunocytochemistry (ICC)
  • Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.

Documents

Further Information

Additional Names:
Protein Jagged-1; CD339; JAG1
Application Note:
ELISA: (direct or indirect: 1:500-1:5,000). Flow Cytometry: (1:20-1:100). Immunohistochemistry: (paraffin sections). Western blot: (1:500-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Background:
Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human Jagged-1.
NCBI Gene ID #:
182
NCBI Official Name:
jagged 1
NCBI Official Symbol:
JAG1
NCBI Organism:
homo sapiens
Physical State:
Liquid
Protein Accession #:
4557679
Protein GI Number:
NP_000205
Research Area:
Cancer
SPECIFICITY:
Recognizes human Jagged-1. Detects a band of ~180kDa by Western blot.
Swissprot #:
P78504
User NOte:
Optimal dilutions for each application to be determined by the researcher.