CD137L Antibody [41B436]

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ProSci
Product Code: PSI-36-030
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-36-030-100ug100ug£577.00
Quantity:
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Overview

Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 41B436
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunocytochemistry (ICC)
  • Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.

Documents

Further Information

Additional Names:
4-1BBL; TNFSF9
Application Note:
ELISA: (direct or indirect: 1:500-1:5,000). Flow Cytometry: (1:1,000). Immunocytochemistry: (see reference Nr. 2). Western blot: (1:2,000). Optimal conditions should be determined individually for each application.
Background:
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human CD137L extracellular domain.
NCBI Gene ID #:
8744
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 9
NCBI Official Symbol:
TNFSF9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
728739
Protein GI Number:
P41273
Research Area:
Cancer,Immunology
SPECIFICITY:
Recognizes extracellular domain of human CD137L. Does not cross-react with mouse CD137L.
Swissprot #:
P41273
User NOte:
Optimal dilutions for each application to be determined by the researcher.