IL-37 Antibody
| Code | Size | Price |
|---|
| PSI-36-313-100ug | 100ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blot (WB)
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Interleukin-1 Family Member 7; IL-1F7; FIL1 zeta; IL-1X; Interleukin-1 Homolog 4; IL-1H4; Interleukin-1 zeta; IL-1 zeta; IL-1RP1; IL1F7; FIL1Z, IL1H4, IL1RP1
Application Note:
ELISA: (direct and indirect: 1:2,000-1:5,000), Immunohistochemistry: (1:50)Immunoprecipitation: (1:500- 1:2,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
IL-37 (Interleukin-37) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human IL-37.
NCBI Gene ID #:
27178
NCBI Official Name:
interleukin 37
NCBI Official Symbol:
IL37
NCBI Organism:
homo sapiens
Physical State:
Liquid
Protein Accession #:
20127524
Protein GI Number:
NP_055254
Research Area:
Cancer,Immunology,Innate Immunity,Obesity
SPECIFICITY:
Recognizes human IL-37. Detects a band of ~30kDa by Western blot.
Swissprot #:
Q9NZH6
User NOte:
Optimal dilutions for each application to be determined by the researcher.