Calreticulin Antibody
| Code | Size | Price |
|---|
| PSI-36-294-100ug | 100ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
CRP55; Calregulin; Endoplasmic Reticulum Resident Protein 60; ERp60; grp60
Application Note:
ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
Calreticulin is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity. It constitutes together with calnexin and ERp57 the ?calreticulin/calnexin cycle? that is responsible for folding and quality control of newly synthesized glycoproteins. Calreticulin has been implicated to play a role in many biological systems, including functions inside and outside the ER, indicating that the protein is a multi-process molecule.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human calreticulin.
NCBI Gene ID #:
811
NCBI Official Name:
calreticulin
NCBI Official Symbol:
CALR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
4757900
Protein GI Number:
NP_004334
Research Area:
Cancer,Immunology,Obesity
SPECIFICITY:
Recognizes human calreticulin. Detects a band of ~60kDa by Western blot.
Swissprot #:
P27797
User NOte:
Optimal dilutions for each application to be determined by the researcher.