FGF-19 Antibody [FG369-1]
| Code | Size | Price |
|---|
| PSI-36-067-100ug | 100ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: FG369-1
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Fibroblast Growth Factor 19
Application Note:
ELISA: (direct or indirect: 1:2,000-1:5,000), Immunohistochemistry: (paraffin sections, 15ug/ml). Western blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Background:
FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human FGF-19.
NCBI Gene ID #:
9965
NCBI Official Name:
fibroblast growth factor 19
NCBI Official Symbol:
FGF19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
11132196
Protein GI Number:
O95750
Research Area:
Cancer,Obesity
SPECIFICITY:
Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.
Swissprot #:
O95750
User NOte:
Optimal dilutions for each application to be determined by the researcher.