BAFF Antibody [1-35-1]

ProSci
Product Code: PSI-36-149
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-36-149-100ug100ug£638.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rat
Antibody Isotype: IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 1-35-1
Regulatory Status: RUO
Target Species: Human
Application: Flow Cytometry
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.

Further Information

Additional Names:
BLyS; TALL-1; CD257; B Cell Activating Factor; TNFSF13B
Background:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sj?gren?s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HA-tagged human BAFF.
NCBI Gene ID #:
10673
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Symbol:
TNFSF13B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
5730097
Protein GI Number:
NP_006564
Purification:
>95% (SDS-PAGE)
Research Area:
Immunology,Innate Immunity
SPECIFICITY:
Recognizes human BAFF.
Swissprot #:
Q9Y275
User NOte:
Optimal dilutions for each application to be determined by the researcher.