BAFF Antibody [4.62]
| Code | Size | Price |
|---|
| PSI-36-119-100ug | 100ug | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a
Antibody Clonality: Monoclonal
Antibody Clone: 4.62
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Functional Study
- Immunoprecipitation (IP)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
BLyS; TALL-1; CD257; B Cell Activating Factor; TNFSF13B
Application Note:
ELISA: (as a detection antibody). Functional Application: Inhibition of human BAFF binding. Immunoprecipitation: (1:200).
Background:
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sj?gren?s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
HA-tagged human BAFF.
NCBI Gene ID #:
10673
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Symbol:
TNFSF13B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
5730097
Protein GI Number:
NP_006564
Purification:
>95% (SDS-PAGE)
Research Area:
Immunology,Innate Immunity,Functional Assays
SPECIFICITY:
Recognizes human BAFF.
Swissprot #:
Q9Y275
User NOte:
Optimal dilutions for each application to be determined by the researcher.