Resistin Antibody (biotin)
| Code | Size | Price |
|---|
| PSI-36-209-50ug | 50ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Application Note:
ELISA: (direct and indirect: 1:5,000-1:10,000). Western Blot: (1:2,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Biotin
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human resistin.
NCBI Gene ID #:
56729
NCBI Official Name:
resistin
NCBI Official Symbol:
RETN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
9966777
Protein GI Number:
NP_065148.1
Research Area:
Obesity
SPECIFICITY:
Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10kDa by Western blot.
Swissprot #:
Q9HD89
User NOte:
Optimal dilutions for each application to be determined by the researcher.