LAG-3 Antibody [11E3] (preservative free)
| Code | Size | Price |
|---|
| PSI-36-106-100ug | 100ug | £686.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 11E3
Regulatory Status: RUO
Target Species:
- Human
- Monkey
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Functional Study
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Immunoprecipitation (IP)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Lymphocyte Activation Gene-3; FDC Protein; CD223
Application Note:
ELISA: (as a capture antibody). Functional Application: Inhibition. Immunohistochemistry: (frozen sections). Immunoprecipitation: (10ug/ml). Western Blot: (5ug/ml).
Background:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Buffer:
Liquid. In PBS containing 10% glycerol. Preservative free formulation.
Concentration:
0.5 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human LAG-3.
NCBI Gene ID #:
3902
NCBI Official Name:
lymphocyte activating 3
NCBI Official Symbol:
LAG3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
251757512
Protein GI Number:
P18627
Purification:
>95% (SDS-PAGE)
Research Area:
Immunology,Innate Immunity,Functional Assays
SPECIFICITY:
Recognizes human and monkey LAG-3.
Swissprot #:
P18627
User NOte:
Optimal dilutions for each application to be determined by the researcher.