Bmf Antibody [9G10]
| Code | Size | Price |
|---|
| PSI-36-173-100ug | 100ug | £638.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 9G10
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Flow Cytometry
- Immunoprecipitation (IP)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Bcl-2-modifying Factor
Application Note:
Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).
Background:
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant mouse Bmf.
NCBI Gene ID #:
90427
NCBI Official Name:
Bcl2 modifying factor
NCBI Official Symbol:
BMF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
15723378
Protein GI Number:
NP_277038
Purification:
>95% (SDS-PAGE)
Research Area:
Apoptosis,Cancer,Immunology
SPECIFICITY:
Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.
Swissprot #:
Q96LC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.