Activin Receptor IIB Antibody
| Code | Size | Price |
|---|
| PSI-36-351-50ug | 50ug | £838.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
ACVR2B; ACTR-IIB; Activin receptor type-2B
Application Note:
ELISA: (1:400) . Western Blot: (1:5000) . Optimal conditions must be determined individually for each application.
Background:
Activin Receptor IIB (ACTR-IIB) is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors (ACVR1, ACVR1B or ACVR1c). ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.
Buffer:
Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide.
Concentration:
500 ug/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant extracellular domain (ecd) of mouse activin receptor IIB.
NCBI Gene ID #:
11481
NCBI Official Name:
activin receptor IIB
NCBI Official Symbol:
Acvr2b
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
114727
Protein GI Number:
P27040
Purification:
Antigen affinity purified.
Research Area:
Cancer,Immunology,Innate Immunity,Neuroscience
SPECIFICITY:
Recognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd.
Swissprot #:
P27040
User NOte:
Optimal dilutions for each application to be determined by the researcher.