CARMA1 Antibody
| Code | Size | Price |
|---|
| PSI-36-321-100ug | 100ug | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
CARD11; Bimp3; Caspase Recruitment Domain-containing Protein 11; CARD-containing MAGUK Protein 1
Application Note:
Western Blot: (1ug/ml).
Background:
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
N-terminal human CARMA1 (aa 1-221 containing the CARD domain).
NCBI Gene ID #:
84433
NCBI Official Name:
caspase recruitment domain family, member 11
NCBI Official Symbol:
CARD11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
16507952
Protein GI Number:
NP_115791.2
Research Area:
Cancer,Innate Immunity
SPECIFICITY:
Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.
Swissprot #:
Q9BXL7
User NOte:
Optimal dilutions for each application to be determined by the researcher.