FOXP3 Antibody
| Code | Size | Price |
|---|
| PSI-36-218-100ug | 100ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Stable for at least 6 months after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
Forkhead Box Protein P3; Scurfin
Application Note:
ELISA: (direct and indirect: 1:2,000-1:10,000). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is TBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
Background:
FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant mouse FOXP3.
NCBI Gene ID #:
20371
NCBI Official Name:
forkhead box P3
NCBI Official Symbol:
Foxp3
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
16905075
Protein GI Number:
NP_473380.1
Research Area:
Cancer,Immunology
SPECIFICITY:
Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot.
Swissprot #:
Q99JB6
User NOte:
Optimal dilutions for each application to be determined by the researcher.