Resistin Antibody [MRES 06]
| Code | Size | Price |
|---|
| PSI-36-003-100ug | 100ug | £524.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rat
Antibody Isotype: IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: MRES 06
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Stable for at least 1 year after receipt when stored at -20˚C.
Documents
Further Information
Additional Names:
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Application Note:
ELISA: (direct or indirect: 1:5,000-1:10,000). Western blot: (1:5,000-1:10,000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Background:
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Buffer:
Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant mouse resistin.
NCBI Gene ID #:
57264
NCBI Official Name:
resistin
NCBI Official Symbol:
Retn
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
12667798
Protein GI Number:
NP_075360.1
Research Area:
Obesity
SPECIFICITY:
Recognizes mouse resistin. Detects a band of ~14kDa by Western blot. Does not cross-react with human resistin.
Swissprot #:
Q99P87
User NOte:
Optimal dilutions for each application to be determined by the researcher.