3-Hydroxykynurenine Transaminase Anopheles gambiae Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-358-50ug | 50ug | £782.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Dry ice
Storage:
Stable for at least 6 months after receipt when stored at -80˚C.
Documents
Further Information
Additional Names:
3-HKT, EC 2.6.1
Application Note:
This recombinant proteins is for research use only.
Background:
The 3-hydroxykynurenine transaminase (3-HKT) gene plays a vital role in the development of malaria parasites by participating in the synthesis of xanthurenic acid, which is involved in the exflagellation of microgametocytes in the midgut of malaria vector species. The 3-HKT enzyme is involved in the tryptophan metabolism of Anophelines. The gene had been studied in the important global malaria vector, Anopheles gambiae.
Biological Activity:
Specific activity towards D,L-3HK: 33 umol/min per mg. Primarily catalyses the pyridoxal 5'-phosphate (PLP)-dependent irreversible transamination of 3-hydroxykynurenine (3-HK) to xanthurenic acid (XA).
Buffer:
In 20mM TRIS-HCl pH 8.0, containing 150mM NaCl and 40uM pyridoxal 5'-phosphate (PLP).
Concentration:
0.5mg/ml (Lot specific)
Fusion Tag:
Tag Free
NCBI Gene ID #:
1272658
NCBI Official Name:
AGAP010387-PA
NCBI Official Symbol:
AgaP_AGAP010387
NCBI Organism:
Anopheles gambiae str. PEST
Physical State:
Liquid
Protein Accession #:
Q7PRG3
Protein GI Number:
74839042
Purity:
>99% (SDS-PAGE)
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q00609