NAD Synthetase M. tuberculosis Recombinant Protein
| Code | Size | Price |
|---|
| PSI-90-366-50ug | 50ug | £782.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Dry ice
Storage:
Stable for at least 6 months after receipt when stored at -80˚C.
Documents
Further Information
Additional Names:
NADE, Glutamine-dependent NAD(+) Synthetase, EC 6.3.5.1
Application Note:
This recombinant proteins is for research use only.
Background:
NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate
Biological Activity:
~0.1 U/mg protein. (Ammonium or glutamine as nitrogen source). One unit is defined as the amount of enzyme that synthesizes 1umol NAD per min.
Buffer:
In 20mM TRIS-HCl, pH 7.8.
Concentration:
0.5mg/ml (Lot specific)
Fusion Tag:
His Tag
Physical State:
Liquid
Protein Accession #:
P0A5L6
Purity:
>98% (SDS-PAGE)
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P16410